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6-[(Z)-Amino(Imino)Methyl]-N-[4-(Aminomethyl)Phenyl]-4-(Pyrimidin-2-Ylamino)-2-Naphthamide

Development stage: Unknown
Modality: Small Molecules

Overview

This compound is a synthetic small molecule with the molecular formula C23H21N7O and a molecular weight of approximately 411.5 g/mol[1][2][3]. It belongs to the class of naphthalene carboxanilides, specifically naphthalene derivatives substituted with pyrimidine and amidine groups[1][2]. The drug is listed as an experimental pharmaceutical in several chemical and pharmacological databases, including DrugBank (DB03082), CHEMBL (CHEMBL104166), and ZINC15[1][2]. Its mechanism of action has not been fully characterized in public sources; however, it has been studied for its interaction with papain-like proteinases, suggesting potential antiviral or protease inhibitory activity relevant to research on SARS-CoV or SARS-CoV‑2 proteins[8]. There are no approved therapeutic indications or marketed formulations for this compound.

Other names: N-[4-(aminomethyl)phenyl]-6-carbamimidoyl-4-[(pyrimidin-2-yl)amino]naphthalene-2-carboxamide6-Carbamimidoyl-4-(pyrimidin-2-ylamino)-naphthalene-2-carboxylic acid (4-aminomethylphenyl)-amide

Targets

PLpro (Papain-like protease)

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